Services

Oncology Services

Mispro now offers a wide range of pre-clinical oncology studies

  • Multiple tumor models in numerous cell lines
    • Xenograft
    • Syngeneic
    • Orthotopic
    • Metastatic
  • Continuous Intravenous Infusion
    • Osmotic pumps
      • 1 day to 6 weeks
      • Possible Treatment: SC, IP, IM, IV, Intranasal and Intratumoral
      • Reference compounds: Gemcitabine, CDDP, 5-FU, Tamoxifen, Dexamethasone, Streptozotocin, Paclitaxel, Doxorubicin, Temozolomide

For more information on specific cell lines and tumor models, contact us.

Continuous Infusion (Osmotic pumps)

  • ALZET® Osmotic pumps
  • Mouse and Rat
  • Tumor Xenograft, pK, MTD, Early Toxicology, Histology studies
  • Subcutaneous, Intraperitoneal, Intragastric Infusions
  • Intravenous Infusions
    • Jugular (mouse and rat)
    • Femoral (rat)
  • 1 day to 6 week continuous infusion
  • Immunodeficient mice:
    • SCID
    • Balb/c nude
    • CD-1 nude
    • Nude (NU/NU)
    • NIH-III
  • Additional mouse models are available upon request
Maintenance of effective plasma level with a 24 hours continuous intravenous infusion in a SCID mice model